反応 #417923

反応方程式

28

methyl 2-hydroxybenzoate

K2CO3

13

1-iodoundec-4Z-ene

→

yellow oil

収率 90.0%

methyl 2-(undec-4Z-enyloxy)benzoate

収率 90.0%

溶媒

DMF

反応条件

後処理

1. 1
   その他After reaction for 8 hours at 90° C.
2. 2
   濃縮the reaction medium is concentrated
3. 3
   洗浄washed with water

実験手順

88 mg of 28 (578 μmol) and 77 mg of K2CO3 (557 mmol) are added to 140 mg of 13 (500 μmol) in anhydrous DMF (2 mL). After reaction for 8 hours at 90° C., the reaction medium is concentrated, taken up in DCM and then washed with water. 137 mg of a yellow oil are obtained, and are chromatographed on silica gel in pentane/ethyl acetate (40/1). 100 mg of a yellow oil are isolated, i.e. a yield of 66%.

出典