反応 #417920

反応方程式

sodium hydroxide

15

methyl 3-(undec-4Z-enyloxy)benzoate

sodium hydroxide

→

yellow oil

収率 96.0%

3-(undec-4Z-enyloxy)benzoic acid

収率 96.0%

溶媒

methanol

反応条件

後処理

1. 1
   温度The solution is refluxed overnight
2. 2
   温度the mixture is refluxed for a further 1 hour 30 minutes
3. 3
   その他After evaporating off the solvent
4. 4
   抽出extracted with DCM

実験手順

4 mL of 1 N sodium hydroxide solution (4.0 mmol) are added portionwise to 1.14 g of 15 (3.74 mmol) in methanol (30 mL). The solution is refluxed overnight. A further 4 mL of 1 N sodium hydroxide solution are added, and the mixture is refluxed for a further 1 hour 30 minutes. After evaporating off the solvent, the reaction medium is acidified with 0.5 N HCl and extracted with DCM. 1.04 g of a yellow oil are obtained, i.e. a yield of 96%.

出典