反応 #41583

反応方程式

4-(2-cyanopyridin-3-yloxy)-5-(6-methanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine

5-(2-cyanopyridin-3-yloxy)-6-(6-methanesulfonyl-pyridin-3-yloxy)-2-pyridin-2-yl-1H-benzimidazole

1H-pyrazole-3-carboxaldehyde

→

5-(2-Cyanopyridin-3-yloxy)-2-(1H-pyrazol-3-yl)-6-(6-methanesulfonyl-pyridin-3-yloxy)-1H-benzimidazole

反応条件

後処理

1. 1
   その他The entitled compound was obtained as a colorless solid in the same method as in Example 202 or in accordance with the method

実験手順

The entitled compound was obtained as a colorless solid in the same method as in Example 202 or in accordance with the method or by combining it with an ordinary method but using 4-(2-cyanopyridin-3-yloxy)-5-(6-methanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine obtained in Example 218 (step 3) and 1H-pyrazole-3-carboxaldehyde.

出典