反応 #41510

反応方程式

epichlorohydrin

formic acid

dimethylaminopropylamine

benzylamine

→

Epichlorohydrin dimethylaminopropylamine benzylamine

溶媒

water

water

water

反応条件

後処理

1. 1
   温度while heating to 85° C.
2. 2
   その他stirring at 85° C.
3. 3
   温度The reaction mixture is cooled

実験手順

1 020 g (10 mol) of dimethylaminopropylamine and 267.5 g (2.5 mol) of benzylamine are mixed in 1 519.1 g of water. The solution/suspension is heated to 50° C. Thereafter, 931 ml of epichlorohydrin (1 098.4 g/l 1.875 mol) are added dropwise at a rate of 16 ml/min while heating to 85° C., and stirring is effected for two hours at 85° C. The stirring at 85° C. is continued until free alkylating agent is no longer detectable (Preuβmann test). The reaction mixture is cooled, diluted with 2 l of water and brought to a pH of 7.0 with 85% strength formic acid. Further water is added until the solids content is 21%.

出典