反応 #414752

反応方程式

4-chloromethyl-2-cyclobutyl-thiazole

triphenylphosphine

→

[(2-cyclobutyl-4-thiazolyl)methyl]triphenylphosphonium chloride

収率 41.7%

溶媒

toluene

反応条件

後処理

1. 1
   温度was heated
2. 2
   温度to reflux for 16 hr
3. 3
   ろ過The mixture was then filtered

実験手順

A mixture of 4.8 g of 4-chloromethyl-2-cyclobutyl-thiazole, 7.0 g of triphenylphosphine and 125 ml of toluene was heated to reflux for 16 hr and then cooled to room temperature. The mixture was then filtered to yield 4.8 g of [(2-cyclobutyl-4-thiazolyl)methyl]triphenylphosphonium chloride.

出典