反応 #413587

反応方程式

ethyl carbamate

stearyl glycidyl ether

N, N-dimethylbenzylamine

→

5-stearyloxymethyl-2- oxazolidinone

反応条件

後処理

1. 1
   その他The product was purified by silica gel column chromatography (developing solvent, hexane: ethyl acetate=4:1)

実験手順

4.45 g (0.050 mole) of ethyl carbamate was dissolved in 16.3 g (0.050 mole) of stearyl glycidyl ether. After adding 2.0 g of N, N-dimethylbenzylamine and 2.0 g of di-n-butyltin dilaurate, the solution was heated at 160° C. for 1 hour while blowing nitrogen gas into the reaction mixture. The product was purified by silica gel column chromatography (developing solvent, hexane: ethyl acetate=4:1) to give 15.9 g (85% of theory) of 5-stearyloxymethyl-2- oxazolidinone.

出典