反応 #413261

反応方程式

1,6-diaminohexane

γ-butyrolactone

→

1,6-Bis-(1-azacyclopentan-2-onyl)hexane

反応条件

後処理

1. 1
   温度heated to 150°-165° for 22 hours
2. 2
   workup.DISTILLATIONExcess γ-butyrolactone was then distilled off at reduced pressure (80°/2 mm)
3. 3
   workup.ADDITIONThe light brown residue was poured into a crystallization dish where it
4. 4
   ろ過filtered
5. 5
   洗浄the tan powder was washed with chloroform

実験手順

11.62 g (0.1 M) of 1,6-diaminohexane and 21.66 g (0.25 M) of γ-butyrolactone were mixed and heated to 150°-165° for 22 hours. Excess γ-butyrolactone was then distilled off at reduced pressure (80°/2 mm). The light brown residue was poured into a crystallization dish where it immediately solidified. The solid was taken in chloroform, powdered, filtered and the tan powder was washed with chloroform. Yield 22.0 g (87%); melting point 101°-103°.

出典