反応 #410054

反応方程式

methyl (RS)-5-[3-(3-nitro-benzyloxy)phenyl]-5-oxo-4-(2-methylphenyl)pentanoate

→

methyl (RS)-5-[3-(3-aminobenzyloxy)- phenyl]-5-oxo-4-(2-methylphenyl)pentanoate

収率 116.1%

溶媒

methyl acetate

反応条件

後処理

1. 1
   ろ過The mixture is filtered
2. 2
   その他evaporated

実験手順

A solution of methyl (RS)-5-[3-(3-nitro-benzyloxy)phenyl]-5-oxo-4-(2-methylphenyl)pentanoate (1.2 g) in methyl acetate (30 mL) is treated with palladium on carbon catalyst (5%; 200 mg) and shaken under hydrogen at atmospheric pressure and room temperature for 3 hours. The mixture is filtered and evaporated giving methyl (RS)-5-[3-(3-aminobenzyloxy)- phenyl]-5-oxo-4-(2-methylphenyl)pentanoate (1.3 g) in the form of a brown oil.

出典