反応 #40835

反応方程式

triethylaluminum

5-phenyl-6-(4-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid ethyl ester

ethyl 5-phenyl-6-(4-trifluoromethylphenyl)-pyridine-2-carboxylate

Compound 29

ethyl 5-phenyl-6-(4-trifluoromethylphenyl)-pyridine-2-carboxylate

N,N′-dimethylethylenediamine

→

title compound

1-[5-Phenyl-6-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-propan-1-one

溶媒

toluene

反応条件

後処理

1. 1
   その他were reacted

実験手順

Following General Procedure O, 5-phenyl-6-(4-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid ethyl ester (Compound 29, 292 mg, 0.71 mmol) in toluene (5 ml), N,N′-dimethylethylenediamine (DMEDA, 76 mg, 0.86 mmol) and triethylaluminum (2.4 ml, 0.35 mmol, 1 M in hexane) were reacted to produce the title compound as a oil.

出典