反応 #40834

反応方程式

triethylaluminum

6-phenyl-5-(4-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid ethyl ester

ethyl 6-phenyl-5-(4-trifluoromethylphenyl)-pyridine-2-carboxylate

Compound 25

ethyl 6-phenyl-5-(4-trifluoromethylphenyl)-pyridine-2-carboxylate

N,N′-dimethylethylenediamine

→

title compound

1-[6-Phenyl-5-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-propan-1-one

溶媒

toluene

反応条件

後処理

1. 1
   その他were reacted

実験手順

Following General Procedure O, 6-phenyl-5-(4-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid ethyl ester (Compound 25, 94 mg, 0.25 mmol) in toluene (3 ml), N,N′-dimethylethylenediamine (DMEDA, 25 mg, 0.28 mmol) and triethylaluminum (0.7 ml, 0.76 mmol, 1 M in hexane) were reacted to produce the title compound as a oil.

出典