反応 #40804

ord-3bbe9e8d5be141679a7e56b70fc93128

反応方程式

CCOC(=O)c1ccc(-c2ccc(C)cc2)c(-c2ccccc2)n1
ethyl 6-phenyl-5-p-tolyl-pyridine-2-carboxylate
CCOC(=O)c1ccc(-c2ccc(C)cc2)c(-c2ccccc2)n1
Compound 22
CCOC(=O)c1ccc(-c2ccc(C)cc2)c(-c2ccccc2)n1
ethyl 6-phenyl-5-p-tolyl-pyridine-2-carboxylate
→
COC(=O)c1ccc(-c2ccc(C)cc2)c(-c2ccccc2)n1
title compound
COC(=O)c1ccc(-c2ccc(C)cc2)c(-c2ccccc2)n1
Methyl 6-Phenyl-5-p-tolyl-pyridine-2-carboxylate

反応物

CCOC(=O)c1ccc(-c2ccc(C)cc2)c(-c2ccccc2)n1
ethyl 6-phenyl-5-p-tolyl-pyridine-2-carboxylate
CCOC(=O)c1ccc(-c2ccc(C)cc2)c(-c2ccccc2)n1
Compound 22
CCOC(=O)c1ccc(-c2ccc(C)cc2)c(-c2ccccc2)n1
ethyl 6-phenyl-5-p-tolyl-pyridine-2-carboxylate

試薬

O=S(=O)(O)O
H2SO4

溶媒

CO
MeOH

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他were reacted

実験手順

Following General Procedure E, ethyl 6-phenyl-5-p-tolyl-pyridine-2-carboxylate (Compound 22, 70 mg, 0.22 mmol) and conc. H2SO4 (3 drops) in MeOH (3 ml) were reacted to produce the title compound as a yellow solid.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US07728014B2uspto-grants-2010_06