反応 #4074

反応方程式

(S)-2-(6-methoxy-2-naphthyl)propionic acid

hydrogen chloride

→

isobutyl (S)-2-(6-methoxy-2-naphthyl)propionate

溶媒

isobutyl alcohol

反応条件

後処理

1. 1
   workup.DISTILLATIONthe excess alcohol is distilled off in vacuo
2. 2
   その他the residue is purified by chromatography

実験手順

A solution of 300 mg of (S)-2-(6-methoxy-2-naphthyl)propionic acid in 5 ml of isobutyl alcohol is saturated with hydrogen chloride. After 24 hours, the excess alcohol is distilled off in vacuo and the residue is purified by chromatography using an alumina substrate to yield isobutyl (S)-2-(6-methoxy-2-naphthyl)propionate.

出典