反応 #4069

反応方程式

N-bromosuccinimide

methyl phenylacetate

→

title compound

収率 93.1%

Methyl Bromo-Phenylacetate

収率 93.1%

溶媒

carbon tetrachloride

反応条件

後処理

1. 1
   温度to reflux
2. 2
   温度refluxed for about 12 hours
3. 3
   ろ過filtered
4. 4
   濃縮The filtrate was concentrated by evaporation under vacuum

実験手順

In this example, a mixture containing 5.93 g of N-bromosuccinimide, 5.0 g of methyl phenylacetate; and a catalytic amount (about 0.1 g) of benzoyl peroxide in 50 ml of carbon tetrachloride was warmed to reflux and then refluxed for about 12 hours. The mixture was then cooled to about 0° C. and filtered. The filtrate was concentrated by evaporation under vacuum affording 7.1 g of the title compound as an oil.

出典