反応 #4030

反応方程式

p-(5-octylpyridyl)benzoic acid

thionyl chloride

→

p-(5-octylpyridyl)benzoylchloride hydrochloride

収率 96.7%

反応条件

後処理

1. 1
   温度reflux
2. 2
   温度was maintained for 5 hours
3. 3
   その他The surplus thionyl chloride was removed by distillation
4. 4
   その他the product was recrystallized from hexane

実験手順

30 g (0.102 mol) of the resulting p-(5-octylpyridyl)benzoic acid was added to 24.3 g (0.204 mol) of thionyl chloride and reflux was maintained for 5 hours. The surplus thionyl chloride was removed by distillation and the product was recrystallized from hexane to obtain 34.5 g (0.0986 mol) of p-(5-octylpyridyl)benzoylchloride hydrochloride.

出典