反応 #40292

ord-331c9182a33848c096ac46b0d1e7327c

反応方程式

CNC1(c2ccccc2Cl)CCCCC1=O
ketamine
Cc1cccc(C)c1NC1=NCCCS1
xylazine
CCCCCCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
testosterone enanthate
→
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2O
Testosterone

反応物

CNC1(c2ccccc2Cl)CCCCC1=O
ketamine
Cc1cccc(C)c1NC1=NCCCS1
xylazine
CCCCCCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
testosterone enanthate

試薬

なし

溶媒

—
sesame oil

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他at 4 weeks

実験手順

Male AR-97Q mice and their normal littermates were castrated or sham-operated via the abdominal route under ketamine-xylazine anesthesia (50 mg/kg ketamine and 10 mg/kg xylazine, i.p.) at 4 weeks of age. Female AR-97Q mice and their littermates were subcutaneously injected 20 μg of testosterone enanthate dissolved in 20 μl of sesame oil weekly from 4 weeks of age until the end of the analysis. The control mice were given the same amount of sesame oil.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US07727952B2uspto-grants-2010_06