反応 #40264

反応方程式

1,2-dimethyl-1H-benzimidazole

N,N′-(disulfanediyldiethane-2,1-diyl)bis(2-chloroacetamide)

→

white powder

収率 129.8%

1,1′-{disulfanediylbis[ethane-2,1-diylimino(2-oxoethane-2,1-diyl)]}bis(2,3-dimethyl-1H-benzimidazol-3-ium) chloride

収率 129.8%

溶媒

acetonitrile

反応条件

後処理

1. 1
   温度was heated
2. 2
   温度to reflux for 24 h
3. 3
   温度After cooling
4. 4
   ろ過the resulting white solids were collected by filtration
5. 5
   洗浄washed with ethyl acetate and dichloromethane

実験手順

A mixture of compound 1,2-dimethyl-1H-benzimidazole (2.93 g, 20 mmol) and N,N′-(disulfanediyldiethane-2,1-diyl)bis(2-chloroacetamide) (1.53 g, 5 mmol) in 20 ml of acetonitrile was heated to reflux for 24 h. After cooling, the resulting white solids were collected by filtration and washed with ethyl acetate and dichloromethane to afford 1.94 g of a white powder. Analyses were in accordance with the expected structure.

出典