反応 #3856

反応方程式

sodium carbonate

cyanuric chloride

1-[2-(2-butylamino)ethyl]-3,3,5,5-tetramethyl-2-piperazinone

→

2,4-dichloro-6-[1-methylpropyl[2-(3,3,5,5-tetramethyl-2-oxo-1-piperazinyl)ethyl]amino]-1,3,5-triazine

溶媒

acetone

water

water

acetone

water

反応条件

後処理

1. 1
   その他In a 1 liter three-necked flask were placed
2. 2
   その他A white slurry formed which
3. 3
   workup.ADDITIONwhile adding to it dropwise
4. 4
   workup.ADDITIONThe addition

実験手順

In a 1 liter three-necked flask were placed 300 ml of water which was cooled to 1° C. 46.1 g (0.25 mole) of cyanuric chloride was dissolved in 240 ml acetone and added to the water in the flask. A white slurry formed which was stirred while adding to it dropwise, 63.9 g (0.25 mole) of 1-[2-(2-butylamino)ethyl]-3,3,5,5-tetramethyl-2-piperazinone in 60 ml acetone and 13.3 g of sodium carbonate in 60 ml water. The addition took about 30 min.

出典