反応 #3786

反応方程式

1,2-bis(5-bromo-2-methyl-3-thienyl)hexafluorocyclopentene

5-(5-trimethylsilyl-2-thienyl)-2-thienyl boric acid

potassium carbonate

→

hexafluorocyclopentene

収率 35.0%

溶媒

dimethoxyethane

反応条件

後処理

1. 1
   温度the reaction mixture was refluxed for two hours
2. 2
   濃縮It was then concentrated under reduced pressures
3. 3
   抽出extracted with diethylether
4. 4
   洗浄rinsed with water
5. 5
   その他With the diethylether removed under reduced pressures
6. 6
   その他the product was purified by alumina column chromatogram

実験手順

1,2-bis(5-bromo-2-methyl-3-thienyl)hexafluorocyclopentene (1.0 g, 0.002 mol) was dissolved in dimethoxyethane (50 ml), and palladium tetra(triphenylphosphine) (120 mg) was added to the mixture which was stirred for 5 minutes under argon atmosphere. With 5-(5-trimethylsilyl-2-thienyl)-2-thienyl boric acid (1.4 g, 0.006 mol) and an aqueous solution of potassium carbonate (0.1 mol dm-3, 10 ml) were added, the reaction mixture was refluxed for two hours. It was then concentrated under reduced pressures, extracted with diethylether and rinsed with water. With the diethylether removed under reduced pressures, the product was purified by alumina column chromatogram to give 1,2-bis[2-methyl-5{5-trimethylsilyl-2-thienyl)-2-thienyl}-3-thienyl]hexafluorocyclopentene (550 mg, 0.0007 mol).

出典