反応 #3784

反応方程式

1,2-bis(2-methyl-5-trimethylsilyl-3-thienyl)hexafluorocyclopentene

hydrobromic acid

→

1,2-bis(2-methyl-3-thienyl)hexafluorocyclopentene

収率 98.0%

溶媒

chloroform

反応条件

後処理

1. 1
   その他to react for 6 hours under refluxing conditions
2. 2
   その他After the completion of the reaction
3. 3
   洗浄the chloroform layer was washed with an aqueous solution of sodium bicarbonate
4. 4
   その他the chloroform was removed under reduced pressures
5. 5
   その他The reaction product was purified by silicagel column chromatogram

実験手順

1,2-bis(2-methyl-5-trimethylsilyl-3-thienyl)hexafluorocyclopentene (2.16 g, 0.005 mol) was dissolved in chloroform (200 ml) and was allowed to react for 6 hours under refluxing conditions by adding concentrated hydrobromic acid (10 ml) to the solution. After the completion of the reaction, the chloroform layer was washed with an aqueous solution of sodium bicarbonate and the chloroform was removed under reduced pressures. The reaction product was purified by silicagel column chromatogram to give 1,2-bis(2-methyl-3-thienyl)hexafluorocyclopentene (1.8 g, 0.0049 mol).

出典