反応 #3742

反応方程式

2, 3-dicyano-pyrazine

isobutylene

sulfuric acid

→

N-tert-butyl-2-pyrazinecarboxamide

3-cyano-N-tert-butyl-2-pyrazinecarboxamide

溶媒

tert-butyl alcohol

反応条件

後処理

1. 1
   その他can be obtained

実験手順

A compound having the formula (4) can be obtained as follows. The corresponding 2, 3-dicyano-pyrazine is reacted with tert-butyl alcohol or isobutylene in the presence of sulfuric acid to obtain the corresponding N-tert-butyl-2-pyrazinecarboxamide and/or 3-cyano-N-tert-butyl-2-pyrazinecarboxamide. Then, thus obtained corresponding N-tert-butyl-2-pyrazinecarboxamide and/or 3-cyano-N-tert-butyl-2-pyrazinecarboxamide are hydrolyzed under an alkaline condition.

出典