反応 #367273

反応方程式

6-chloro-1-hexanol

mercaptoacetic acid

→

6-(Carboxymethylthio)-1-hexanol

溶媒

NaOH

反応条件

後処理

1. 1
   抽出extracted repeatedly with ethyl acetate
2. 2
   濃縮The combined extracts are concentrated to dryness
3. 3
   その他the residue purified by recrystallization

実験手順

4.5 ml (0.04M) of 6-chloro-1-hexanol is added to a solution of 2.8 ml (0.04M) of mercaptoacetic acid in 120 ml of 1N NaOH. The solution is warmed to about 50° C. for 16 hours, then acidified and extracted repeatedly with ethyl acetate. The combined extracts are concentrated to dryness and the residue purified by recrystallization.

出典