反応 #366874

反応方程式

acrylate

decafluorobenzophenone

trichloroacetic acid

fluorine

→

2,2,2-trichloro-1,1-di(2,3,4,5,6-pentafluorophenyl)-1-ethanol

溶媒

carbinol

carbinol

hexamethylphosphoramide

反応条件

後処理

1. 1
   その他The stirred reaction mixture
2. 2
   温度to warm to room temperature

実験手順

A mixture of 4.9 g of decafluorobenzophenone and 2.7 g of trichloroacetic acid was added to 15 mL of hexamethylphosphoramide. The stirred reaction mixture was maintained at about 0° C. for about 2 hours and then allowed to warm to room temperature and continue stirring at ambient temperature for the next 15 hours. The reaction mixture was characterized by GC and fluorine NMR to show a conversion of approximately 20% to the desired carbinol. This carbinol can be converted to the corresponding acrylate by methods previously described (cf. Example 24).

出典