反応 #3609

反応方程式

4-chloro-o-anisic acid

thionyl chloride

→

desired product

4-Chloro-2-methoxybenzoyl chloride

反応条件

後処理

1. 1
   温度at reflux for 1 hour
2. 2
   その他The volatiles are evaporated in vacuo
3. 3
   その他to give a residue which
4. 4
   濃縮is concentrated from toluene three times
5. 5
   その他dried under vacuum

実験手順

A solution of 2.0 g of 4-chloro-o-anisic acid in 22 ml of thionyl chloride is heated at reflux for 1 hour. The volatiles are evaporated in vacuo to give a residue which is concentrated from toluene three times and dried under vacuum to give 2.0 g of the desired product as a residue.

出典