反応 #358693

反応方程式

Oxalyl chloride

4,5-dibromo-2-furoic acid

dimethylformamide

→

title compound

4,5-Dibromo-furan-2-carbonyl chloride

溶媒

dichloromethane

反応条件

後処理

1. 1
   濃縮concentrated in vacuo
2. 2
   workup.DISSOLUTIONThe residue was re-dissolved in dichloromethane
3. 3
   濃縮concentrated in vacuo

実験手順

Oxalyl chloride (10.4 ml, 0.12 mol) was added to a suspension of 4,5-dibromo-2-furoic acid (27 g, 0.1 mol) in dichloromethane (300 ml) containing dimethylformamide (0.1 ml). The mixture was stirred at room temperature for 4 h and then concentrated in vacuo. The residue was re-dissolved in dichloromethane and concentrated in vacuo; this was repeated to give the title compound which was used directly in the following step.

出典