反応 #355438

反応方程式

compound

9-Anilino-7-methyl-1H-imidazo[4,5-f]quinoline Hydrochloride

3-methylmercaptoaniline

→

9-(3-Methylthioanilino)-7-methyl-1H-imidazo[4,5-f]quinoline Hydrochloride

溶媒

dimethylformamide

反応条件

後処理

1. 1
   workup.ADDITIONA mixture of 21.7 g
2. 2
   温度It was chilled
3. 3
   ろ過filtered
4. 4
   洗浄washed with ether
5. 5
   その他air-dried
6. 6
   その他to give 29 g

実験手順

A mixture of 21.7 g. (0.1 m.) of the compound of Example I, C., 13.9 g. (0.1 m.) of 3-methylmercaptoaniline and 250 ml. of dimethylformamide was refluxed overnight with stirring. It was chilled, filtered, washed with ether and air-dried to give 29 g. m.p. 310°-313°C.

出典