反応 #350559

ord-8bef3a7975ed42dc885d5b77b6c6816b

反応方程式

CCCC(O)CC(=O)O
3-hydroxy hexanoic acid
CCC[C@@H](O)CC(=O)O
(R)-3-hydroxyhexanoic acid
CCC[C@H](O)CC(=O)O
(S)-3-hydroxyhexanoic acid

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他The reaction times
  2. 2
    その他The conversion of 20-80% is attained within the above preferable reaction times

実験手順

The reaction times are suitably 1 to 1000 hours, preferably 1 to 200 hours. Namely, the reaction time depends on the kind of the racemic esters of 3-hydroxy hexanoic acid which are starting materials. The conversion of 20-80% is attained within the above preferable reaction times. In this case, in the reaction of the conversion of 50% or less, (R)-3-hydroxyhexanoic acid having optical purity over 90% ee is obtained, while in the reaction of the conversion of 50% or more, (S)-3-hydroxyhexanoic acid having optical purity over 90% ee is obtained.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US05643793uspto-grants-1997_07