反応 #349988

ord-7449d7e547074f82a03627cc30393c1b

反応方程式

Cl.c1ccncc1
pyridine hydrochloride
Cl
HCl
CC(C)CC1CCCC(=O)C1
3-isobutyl-cyclohexanone
CC(=O)C(=O)[O-].[Na+]
sodium pyruvate
CC(C)Cc1ccc(C(C)C(=O)O)cc1
p-isobutylhydratropic acid

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他to give
  2. 2
    workup.ADDITIONa mixture of condensation products
  3. 3
    その他condensation products

実験手順

The process according to claim 1, wherein 3-isobutyl-cyclohexanone and sodium pyruvate are heated in a HCl and acetic acid solution to give a mixture of condensation products and said condensation products are heated for 4 to 5 hours with pyridine hydrochloride to give p-isobutylhydratropic acid.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US04154962uspto-grants-1979_05