反応 #349269

反応方程式

2-iodo-3-phenyl-7-benzofuranacetic acid

cyclohexene

dinitrogen tetroxide

→

2-nitro-3-phenyl-7-benzofuranacetic acid

溶媒

chloroform

chloroform

反応条件

後処理

1. 1
   洗浄washed with water
2. 2
   洗浄washed with water twice
3. 3
   その他dried
4. 4
   その他evaporated

実験手順

To a solution of 2.2 g. (5.8 mmoles) of 2-iodo-3-phenyl-7-benzofuranacetic acid, 1 g. (5.8 mmoles) of cyclohexene and 175 ml. of chloroform is added 0.9 g. (10 mmoles) of dinitrogen tetroxide in 15 ml. of chloroform. The mixture is stirred for 20 hours, washed with water and made basic with sodium hydroxide. The chloroform layer is acidified with hydrochloric acid, washed with water twice and dried, then evaporated to provide 2-nitro-3-phenyl-7-benzofuranacetic acid, identical to the sample prepared in Example 2.

出典