反応 #348014

反応方程式

indole-3-carboxylic acid

1-bromononane

potassium carbonate

→

nonyl indole-3-carboxylate

溶媒

N,N-dimethylformamide

反応条件

後処理

1. 1
   ろ過After insoluble materials were filtered off
2. 2
   workup.ADDITIONthe filtrate was diluted with ethyl acetate
3. 3
   洗浄washed with water and brine
4. 4
   乾燥dried over magnesium sulfate
5. 5
   濃縮concentrated
6. 6
   その他The solid was collected
7. 7
   洗浄washed with hexane

実験手順

A mixture of indole-3-carboxylic acid, 1-bromononane and potassium carbonate in N,N-dimethylformamide was stirred at room temperature for 15 hours. After insoluble materials were filtered off, the filtrate was diluted with ethyl acetate, washed with water and brine, dried over magnesium sulfate and concentrated. The solid was collected and washed with hexane to give nonyl indole-3-carboxylate.

出典