反応 #347486

ord-4cc0dbd571f043d7ae61b13835e0f4ed

反応方程式

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C(C)C=C4NC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
compound 29
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C(C)C=C4NC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
7-Methyl-4-aza-cholest-5-en-3-one
→
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C(C)CC4NC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
title compound 30
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C(C)CC4NC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
7-Methyl-4-aza-Cholestan-3-one

反応物

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C(C)C=C4NC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
compound 29
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C(C)C=C4NC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
7-Methyl-4-aza-cholest-5-en-3-one

試薬

なし

溶媒

CC(=O)O
HOAc

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

Following the analogous general procedure of Example 8, compound 29 was catalytically hydrogenated in HOAc to yield the title compound 30.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US05527807uspto-grants-1996_06