反応 #346430

反応方程式

5-(m-chlorobenzylsulfinyl)-2-pyridinecarboxylic acid methyl ester

sodium hydroxide methanol

→

sodium 5-(m-chlorobenzylsulfinyl)-2-pyridinecarboxylate

反応条件

後処理

1. 1
   workup.ADDITIONis added until dissolution
2. 2
   温度The solution is heated at the steam bath for 10 minutes
3. 3
   その他It is evaporated
4. 4
   ろ過the solution filtered
5. 5
   温度the filtrate cooled
6. 6
   その他the precipitate formed
7. 7
   その他collected

実験手順

To the stirred mixture of 9 g of 5-(m-chlorobenzylsulfinyl)-2-pyridinecarboxylic acid methyl ester and 40 ml of N aqueous sodium hydroxide methanol is added until dissolution occurs. The solution is heated at the steam bath for 10 minutes and stirred overnight at room temperature. It is evaporated, the residue taken up in the minimum amount of hot water, the solution filtered, the filtrate cooled and the precipitate formed collected, to yield the sodium 5-(m-chlorobenzylsulfinyl)-2-pyridinecarboxylate.

出典