反応 #346247

反応方程式

1-decanol

mesyl chloride

→

decyl methylsulfonate

溶媒

n-hexane

collidine

反応条件

後処理

1. 1
   workup.ADDITIONpoured onto ice
2. 2
   抽出The reaction mixture is extracted with ether
3. 3
   洗浄the ether extracts are washed with 10% hydrochloric acid
4. 4
   乾燥dried over anhydrous sodium sulfate
5. 5
   その他the solvent removed under reduced pressure
6. 6
   その他to leave an oil which
7. 7
   温度upon cooling
8. 8
   温度cooled

実験手順

To a cooled solution of 158.3 grams of 1-decanol in 1.0 liter of collidine is added dropwise 126 grams of mesyl chloride. The resulting mixture is stirred at room temperature for 1.5 hours and then poured onto ice. The reaction mixture is extracted with ether and the ether extracts are washed with 10% hydrochloric acid. The ether extracts are combined, dried over anhydrous sodium sulfate, and the solvent removed under reduced pressure to leave an oil which solidifies upon cooling. The oil is dissolved in n-hexane and cooled to yield as crystals, decyl methylsulfonate.

出典