反応 #345559

反応方程式

tetrabutylammonium hydroxide

Methylphenylacetate

→

tetra-n-butyl ammonium methylphenylacetate

溶媒

toluene

反応条件

後処理

1. 1
   温度heated to +75° C. to +85° C
2. 2
   workup.DISTILLATIONSimultaneously an azeotrope of toluene-water was distilled out slowly over a period of 3 hours
3. 3
   workup.DISTILLATIONAfter all toluene had distilled over, the flask
4. 4
   その他A solid product separated out
5. 5
   洗浄which was repeatedly washed with dry hexane

実験手順

In a similar apparatus as described in example 2, 7.7 mmoles of tetrabutylammonium hydroxide (20% solution in toluene/methanol) in 40 ml of dry toluene was taken and heated to +75° C. to +85° C. Methylphenylacetate (9.0 mmoles) was slowly added. Simultaneously an azeotrope of toluene-water was distilled out slowly over a period of 3 hours. After all toluene had distilled over, the flask was cooled to room temperature slowly. A solid product separated out, which was repeatedly washed with dry hexane. The initiator (tetra-n-butyl ammonium methylphenylacetate) thus formed was dried in vacuum and stored at room temperature under nitrogen or argon.

出典