反応 #345480

反応方程式

4-amino-1-[9,10-dihydro-9,10-methanoanthracen-9-ylmethyl]piperidine

2-chlorophenylacetic acid

→

title compound

N-(1-[9,10-Dihydro-9,10-methanoanthracen-9-ylmethyl]-4-piperidyl)-2-(2-chlorophenyl)acetamide

反応条件

実験手順

Using a procedure similar to that described in Example 6 except starting with 4-amino-1-[9,10-dihydro-9,10-methanoanthracen-9-ylmethyl]piperidine and 2-chlorophenylacetic acid, the title compound was obtained as a pink solid (71%), mp 212.0°-14.0° C.; MS(CI): 457 (M+H); NMR (300 MHz,DMSO-d6): 1.38(m, 2H), 1.70(m, 2H), 2.28(m, 2H), 2.46(s, 2H), 2.93(m, 2H), 3.30(m,submerged, 2H), 3.54(m, 3H), 4.31(s, 1H), 6.87-6.96(m, 4H), 7.17-7.41(m, 8H), 7.96(d, 1H, J=7.7 Hz).

出典