反応 #343977

反応方程式

lactic acid

decyl alcohol

sulfuric acid

→

clear colorless liquid

収率 13.9%

Decyl Lactate

収率 13.9%

溶媒

toluene

反応条件

後処理

1. 1
   その他water was collected as the reaction
2. 2
   洗浄by washing three times with 50 ml saturated sodium bicarbonate solution
3. 3
   その他The organic layer was collected
4. 4
   乾燥dried over magnesium sulfate
5. 5
   workup.DISTILLATIONDecyl lactate was distilled under high vacuum

実験手順

A 500 ml one neck round bottom flask equipped with a Dean Stark trap, condenser and nitrogen inlet-outlet was charged with 22.52 g (0.75 moles) lactic acid, 47.46 g (0.98 moles) decyl alcohol, 3 ml sulfuric acid and 220 mL toluene. The mixture was heated to 145° C. for 20 hours and water was collected as the reaction proceeded. The acid was neutralized by washing three times with 50 ml saturated sodium bicarbonate solution. Approximately 50 ml ether was needed to break the emulsion. The organic layer was collected and dried over magnesium sulfate. Decyl lactate was distilled under high vacuum to yield 24.03 g (12.4% yield) of clear colorless liquid. According to GC the product is 97.78% pure.

出典