反応 #343976

反応方程式

methyl lactate

decyl alcohol

NaOH

→

crude mixture

収率 180.9%

Decyl Lactate

収率 180.9%

溶媒

methanol

反応条件

後処理

1. 1
   その他A 250 mL round bottom flask equipped with a spin bar
2. 2
   workup.DISTILLATIONa distillation column
3. 3
   抽出extracted with ether
4. 4
   乾燥The organic layer was dried over MgSO4
5. 5
   ろ過filtered
6. 6
   その他dried in vacuo

実験手順

A 250 mL round bottom flask equipped with a spin bar and a distillation column was charged with 100 g (0.96 moles) of methyl lactate, 304.1 g (1.92 moles) of decyl alcohol, and 500 mg of H2SO4. The reaction was heated until methanol formation ceased. The reaction was then neutralized with 0.1N NaOH (100 mL) and extracted with ether. The organic layer was dried over MgSO4, filtered and dried in vacuo to give 400 g of crude mixture. The fractional distillation was carried out three times to give 98.5 g (45% yield, 100% pure by GC) of a clear colorless oil.

出典