反応 #343292

反応方程式

5-ethyl-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolidinyl)nicotinic acid

sodium hydroxide

→

sodium 5-ethyl-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolidinyl)nicotinate

溶媒

methanol

反応条件

後処理

1. 1
   その他The solvent is removed
2. 2
   その他to give a solid which
3. 3
   その他is dried in a vacuum oven at 60° C. for two days
4. 4
   その他darkens at 230° C.
5. 5
   その他decomposes at 247°-250° C.

実験手順

To 1.0 g 5-ethyl-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolidinyl)nicotinic acid is added a solution of 0.1498 g sodium hydroxide in 20 mL absolute methanol. The mixture is stirred under nitrogen at room temperature overnight. The solvent is removed to give a solid which is dried in a vacuum oven at 60° C. for two days. The thus-formed sodium 5-ethyl-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolidinyl)nicotinate darkens at 230° C. and decomposes at 247°-250° C.

出典