反応 #343008

反応方程式

product

2-(4,5-Dihydro-4-methyl-5-oxo-1,3,4-oxadiazol-2-yl)benzenesulfonamide

phenyl(4-methyl-6-methoxy-1,3,5-triazin-2-yl)carbamate

DBU

→

subject compound

収率 45.2%

4,5-Dihydro-4-methyl-5-oxo-1,3,4-oxadiazol-2-yl-N[(4-methyl-6-methoxy-1,3,5-triazin-2-yl)aminocarbonyl]benzenesulfonamide

収率 45.2%

溶媒

p-dioxane

反応条件

後処理

1. 1
   その他The isolated crude solid
2. 2
   その他was purified
3. 3
   洗浄by slurry-washing with 10 l of warm acetonitrile

実験手順

By the procedure of Example 5, 0.4 g of the product of Example 4 was reacted with 0.41 g of phenyl(4-methyl-6-methoxy-1,3,5-triazin-2-yl)carbamate and 0.24 g of "DBU" in 10 ml of p-dioxane. The isolated crude solid was purified by slurry-washing with 10 l of warm acetonitrile to yield 0.3 g of the subject compound; m.p. 198°-200° C.

出典