反応 #341316

反応方程式

4-Bromophenol

potassium carbonate

benzyl bromide

→

4-benzyloxybromobenzene

溶媒

acetone

ethyl acetate

反応条件

後処理

1. 1
   温度The reaction was refluxed under a nitrogen atmosphere
2. 2
   温度After 5-6 hours reflux
3. 3
   洗浄This solution was washed with water
4. 4
   乾燥dried over anhydrous magnesium sulfate
5. 5
   その他evaporated to dryness
6. 6
   その他A white fluffy solid was obtained

実験手順

4-Bromophenol (2 g, 0.0116 mol) in acetone (40 mL) was treated with potassium carbonate anhydrous (1.91 g, 1.2 equivalents) and benzyl bromide (1.44 mL, 1.05 equivalents). The reaction was refluxed under a nitrogen atmosphere. After 5-6 hours reflux, the reaction was cooled to room temperature and diluted with an equal volume of ethyl acetate. This solution was washed with water, dried over anhydrous magnesium sulfate and evaporated to dryness. A white fluffy solid was obtained. Yield=2.36 g (73%).

出典