反応 #341115

ord-b75353f283ab47f9b1d87332a24eb17b

反応方程式

C[C@H]1CC[C@H](N(C(=O)Nc2ncc(Cl)s2)C2CCNCC2)CC1
3-(5-chloro-thiazol-2-yl)-1-(trans-4-methyl-cyclohexyl)-1-piperidin-4-yl-urea
O=C(O)CCCCC(=O)O
adipic acid
O=C(O)CCCCC(=O)N1CCC(N(C(=O)Nc2ncc(Cl)s2)C2CCCCC2)CC1
6-{4-[3-(5-Chloro-thiazol-2-yl)-1-cyclohexyl-ureido]-piperidin-1-yl}-6-oxo-hexanoic acid

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他Prepared

実験手順

Prepared as described in general procedure (G) using 3-(5-chloro-thiazol-2-yl)-1-(trans-4-methyl-cyclohexyl)-1-piperidin-4-yl-urea and adipic acid.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US07872139B2uspto-grants-2011_01