反応 #335661

反応方程式

selenium dioxide

water

2-acetylfuran

→

α-oxo-2-furanacetaldehyde

溶媒

dioxane

反応条件

後処理

1. 1
   温度the mixture was refluxed for 4 hours
2. 2
   ろ過filtered
3. 3
   その他evaporated
4. 4
   workup.DISSOLUTIONThe residue was dissolved in dichloromethane
5. 5
   workup.ADDITIONtreated with activated charcoal
6. 6
   ろ過filtered
7. 7
   その他evaporated
8. 8
   workup.DISTILLATIONThe residue was distilled

実験手順

A mixture of 55 g of selenium dioxide, 11 ml of water and 150 ml of dioxane was heated at 55° C. until solution was complete. A 55 g portion of 2-acetylfuran was added, the mixture was refluxed for 4 hours, then filtered and evaporated. The residue was dissolved in dichloromethane, treated with activated charcoal, filtered and evaporated. The residue was distilled, giving 28 g of α-oxo-2-furanacetaldehyde.

出典