反応 #331844

反応方程式

methyl 2-amino-5-(1-methylethyl)-1,3-thiazole-4-carboxylate

hydrochloric acid

→

title compound

収率 117.3%

2-Amino-5-(1-methylethyl)-1,3-thiazole-4-carboxylic acid

収率 117.3%

溶媒

1,4-dioxane

反応条件

後処理

1. 1
   その他The mixture was evaporated in vacuo

実験手順

To a solution of methyl 2-amino-5-(1-methylethyl)-1,3-thiazole-4-carboxylate (220 mg) (for example, available from ABCR) in 1,4-dioxane (5 ml) was added 2M hydrochloric acid (5 ml) and the mixture heated at 110° C. for 72 h. The mixture was evaporated in vacuo to give the title compound (240 mg) as a pale yellow solid.

出典