反応 #321643

反応方程式

benzo[b]thiophene-2-boronic acid

N-(5-bromothiophene-2-sulfonyl)pyrrole

→

N-[5-(benzo[b]thien-2-yl)thiophene-2-sulfonyl]pyrrole

収率 68.0%

反応条件

後処理

1. 1
   その他Purification by column chromatography

実験手順

N-[5-(benzo[b]thien-2-yl)thiophene-2-sulfonyl]pyrrole was prepared in the same manner as described in Example 32C from benzo[b]thiophene-2-boronic acid (426 mg, 2.39 mmol) and N-(5-bromothiophene-2-sulfonyl)pyrrole (700 mg, 2.39 mmol). Purification by column chromatography using 2% ethyl acetate/hexanes gave the pure sulfonamide in 68% yield as a brownish-red solid.

出典