反応 #321640

反応方程式

2-ethylthiophene-5-boronic acid

N-(5-bromothiophene-2-sulfonyl)pyrrole

→

N-[5-(5-ethyl-2-thienyl)thiophene-2-sulfonyl]pyrrole

反応条件

後処理

1. 1
   その他Purification by column chromatography

実験手順

N-[5-(5-ethyl-2-thienyl)thiophene-2-sulfonyl]pyrrole was prepared in the same manner as described in Example 32C from 2-ethylthiophene-5-boronic acid (411 mg, 2.64 mmol) and N-(5-bromothiophene-2-sulfonyl)pyrrole (700 mg, 2.39 mmol). Purification by column chromatography using 2% ethyl acetate/hexanes gave 6.30 mg of the pure product as a dark brown solid (90% yield).

出典