反応 #321638

反応方程式

2-methylthiophene-5-boronic acid

N-(5-bromothiophene-2-sulfonyl)pyrrole

→

N-[5-(5-methyl-2-thienyl)thiophene-2-sulfonyl]pyrrole

収率 72.0%

反応条件

後処理

1. 1
   その他Purification by column chromatography

実験手順

N-[5-(5-methyl-2-thienyl)thiophene-2-sulfonyl]pyrrole was prepared in the same manner as described in Example 32C from 2-methylthiophene-5-boronic acid and N-(5-bromothiophene-2-sulfonyl)pyrrole. Purification by column chromatography using 2% ether/hexanes gave the pure sulfonamide in 72% yield as a white solid.

出典