反応 #321628

反応方程式

4-methyl-phenylboronic acid

N-(5-bromothiophenesulfonyl)pyrrole

→

N-[5-(4-methylphenyl)thiophene-2-sulfonyl]pyrrole

反応条件

後処理

1. 1
   その他N-[5-(4-methylphenyl)thiophene-2-sulfonyl]pyrrole was prepared in the same manner
2. 2
   その他Purification by column chromatography

実験手順

N-[5-(4-methylphenyl)thiophene-2-sulfonyl]pyrrole was prepared in the same manner as described in Example 32C using 4-methyl-phenylboronic acid and N-(5-bromothiophenesulfonyl)pyrrole. Purification by column chromatography using 2% ethyl acetate/hexanes gave N-[5-(4-methylphenyl)thiophene-2-sulfonyl]pyrrole as a pale yellow solid in 77% yield.

出典