反応 #321502

反応方程式

4-ethylphenylboronic acid

N-(5-bromothiophenesulfonyl)pyrrole

→

N-[5-(4-ethylphenyl)thiophene-2-sulfonyl]pyrrole

収率 81.0%

反応条件

後処理

1. 1
   その他Purification by column chromatography

実験手順

N-[5-(4-ethylphenyl)thiophene-2-sulfonyl]pyrrole was prepared, in the same manner as described in Example 32C, from 4-ethylphenylboronic acid and N-(5-bromothiophenesulfonyl)pyrrole. Purification by column chromatography using 10% ethyl acetate/hexanes gave the pure sulfonamide as a tan solid in 81% yield.

出典