反応 #318856

反応方程式

barium sulfate

2,4-difluorobenzoylchloride

→

2,4-difluorobenzaldehyde

溶媒

decahydronaphthalene

反応条件

後処理

1. 1
   その他The reaction was purged with H2 for 0.25 hour
2. 2
   workup.ADDITIONHydrogen was dispersed through the system for 6 hours

実験手順

30 ml (27 g) of decahydronaphthalene and 0.5 g (2.3×10-4 ml) of a catalyst of 5% palladium on a barium sulfate support were added to the flask containing the 2,4-difluorobenzoylchloride. The reaction was purged with H2 for 0.25 hour, then the temperature was raised to 130° C. Hydrogen was dispersed through the system for 6 hours. The product 2,4-difluorobenzaldehyde was isolated as a colorless liquid. Yield 9.8 g (82%).

出典