反応 #316574

反応方程式

7-bromo-4-tert-butyl-4,5-dihydropyrrolo[1,2-a]quinoxaline

m-anisoyl chloride

→

7-Bromo-4-tert-butyl-5-(3-methoxybenzoyl)-4,5-dihydropyrrolo[1,2-a]quinoxaline

反応条件

後処理

1. 1
   その他The product was purified via Biotage Horizon® (25S, silica, gradient from 5% EtOAc/hexane to 40% EtOAc/hexane)
2. 2
   その他isolated as a white foam

実験手順

7-Bromo-4-tert-butyl-5-(3-methoxybenzoyl)-4,5-dihydropyrrolo[1,2-a]quinoxaline was prepared from 7-bromo-4-tert-butyl-4,5-dihydropyrrolo[1,2-a]quinoxaline and m-anisoyl chloride according to the procedure of Example 106, Step 2. The product was purified via Biotage Horizon® (25S, silica, gradient from 5% EtOAc/hexane to 40% EtOAc/hexane) and isolated as a white foam. MS (ESI) m/z 439/441 ([M+H]+); HRMS: calcd for C23H23BrN2O2, 438.0943; found (ESI+), 439.10084.

出典