反応 #3164

反応方程式

2-(aminoethoxy) ethanol

hexahydrophthalic anhydride

→

N-(2-hydroxyethoxyethyl)hexahydrophthalimide

収率 96.0%

溶媒

ethanol

反応条件

後処理

1. 1
   その他A 500-ml, two necked flask was equipped with a magnetic stirring bar
2. 2
   温度heating mantle and condenser
3. 3
   workup.ADDITIONAfter the addition
4. 4
   温度was refluxed for 12 hours
5. 5
   その他The ethanol was removed with a rotoevaporator

実験手順

A 500-ml, two necked flask was equipped with a magnetic stirring bar, heating mantle and condenser. The flask was charged with 51 g of 2-(aminoethoxy) ethanol (0.49 mol.) and 250 ml of ethanol. Next, 75 g of hexahydrophthalic anhydride (0.49 mol.) was slowly added to the flask. After the addition was complete the reaction was refluxed for 12 hours. The IR spectrum indicated the reaction was complete. The ethanol was removed with a rotoevaporator to yield 113 g (96%) of N-(2-hydroxyethoxyethyl)hexahydrophthalimide.

出典